Abstract: Marine wide-azimuth high-efficient acquisition using multi-vessel and multi-cable network is increasingly noticed by petroleum companies to reduce costs through higher productivity and to improve seismic data quality through denser source sampling. One major drawback of this method is the crosstalk noise generated by the simultaneous source. It is essential to understand the characteristics of interference from this type of noise and identify proper acquisition techniques and processing workflows to reduce its impact on image quality. First, 3D finite difference modelling was performed at a complex subsurface and then data were blended by combining the synthetic shots to simulate a four-boat wide-azimuth marine seismic survey. At last, a series of processing techniques were applied to optimally de-blend the data. These techniques were tested in several different domains and also in a cascaded manner.