Abstract: The Ⅴ Oil Group of Kenli 6-A Oilfield in the lower Minghuazhen Formation (MF) of the Neogene is one of the key strata for shallow exploration and development in the Bohai Sea. The MF features shallow water delta deposits widely developed. However, systematic research on its evolution and controlling factors lacks, leading to poor understanding of the spatial distribution and connectivity of sand bodies. Based on the interface identification of seismic, drilling and logging, the Ⅴ Oil Group could be divided into five subgroups corresponding to four fourth-order sequences, based on which a high-precision sequence stratigraphic framework was established. The sedimentary evolution of the Ⅴ Oil Group were reproduced by high-precision isochronous three-dimensional stratigraphic slicing, showing characteristics of large distributary channels in the early Ⅴ-5 subgroup, small distributary channels in the maximum invasion period in the Ⅴ-4 subgroup, the medium-scale channels (channel complexes ) in the Ⅴ-2 and Ⅴ-3 subgroups, and the co-existence of large channels and small channels in the late Ⅴ-1 sub group. The sedimentary evolution and sand body distribution were mainly controlled by the paleogeomorphology and stratigraphic sequence and distributed in an orderly manner. Different paleogeomorphology units on the plane controlled the scale of the channel. The large channel distributed mainly in the depression area during the Ⅴ-1 and Ⅴ-5 periods, the medium channel distributed in the root of the fault terrace during the Ⅴ-2 and Ⅴ-3 periods, and the small distributary channel distributed in the higher part of the sequence. In the vertical direction, the sequence controlled the change of channel, in which large channels developed at the bottom of the second- or third-order sequence, the medium-scale channel developed at the bottom and top of the fourth-order sequence, and small distributary channel developed near the fourth-order transgressive surface. It is predicted that the potentially favorable sand bodies are large channel deposits in the study area, which will effectively guide the subsequent exploration deployment and well location optimization, and enrich the understanding of the sedimentary model of the Neogene shallow-water delta in the Bohai Sea.