Abstract: Due to the influence of ghost reflection (ghost wave), the imaging resolution of offshore horizontal streamer seismic data is reduced, which directly affects the accuracy and precision of seismic data interpretation in the description of offshore oil and gas reservoirs. The existing ghost suppression methods usually treat the source and cable ghost waves separately, and do not consider the effect of offset on the ghost wave delay. This paper presents a technique to suppress ghost wave from source, cable and source-cable simultaneously when the delay of ghost wave varies with offset. The experimental results of theoretical model and real data processing show that the proposed method is stable and can effectively suppress the ghost wave in offshore horizontal streamer seismic data, recover the energy of the frequency band affected by the ghost wave notch, and improve the quality of imaging data.