Abstract: Based on the existing in-situ measurement data and the results of sampling analysis, the correlation between sediment physicochemical composition and shear strength was identified by using regression analysis method. The results show that the deep-sea sediments are mainly composed of silty soil and organic clay, which are the characterized by high water content, large pore ratio and low density. In addition, the water content and pore ratio of deep-sea sediment gradually decrease with the increase of burial depth, while the wet density and shear strength increase. There is a good correlation between physical parameters and shear strength, water content, density, pore ratio and shear strength. The correlation of shear strength is obvious, in which the density is proportional to the shear strength, while the water content and pore ratio are inversely proportional to the shear strength; th multivariable regression analysis equation with water content, density and pore ratio as independent variables can better express the correlation between physical properties of sediment and shear strength.